Yale research looks at mutations in tumor genes to tell us what causes cancer

It’s well known that exposure to ultraviolet rays from sunlight can cause melanoma and that smoking is closely linked to lung cancer.

Two Yale University researchers have made strong genetic arguments for these links, as well as for 22 other types of cancer. By looking at which mutations in our genes are likely to cause certain types of cancer, they can determine which are more preventable and which are more related to factors we can’t control, such as cancer. B. aging.

“There’s some sort of signature in the tumor’s genome that tells you what kind of mutations have been introduced into the genome,” said Jeffrey Townsend, a professor of biostatistics at the Yale School of Public Health.